3.9 years ago by
Double check that your inputs are both in the correct format (content-wise, in particular quality score scaling) and are assigned the proper datatype attribute (.fastqsanger). It is very important that both are true (an improperly assigned datatype will just lead to problems later on - meaning that you will have to start over!).
Exact how-to help is here in our wiki:
More help for similar questions is also in prior Q&A - try a search here if you wish to read more details.
Best, Jen, Galaxy team