Question: Variant annotation for bacterial genome
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gravatar for aurelie.renvoise
4.4 years ago by
aurelie.renvoise • 10 wrote:

I have a vcf file, and I wish to  identify whether SNPs cause protein coding changes and the amino acids that are affected. I have .gbk, .gff, and .ptt files for my reference genome (bacterial one), but I don't know how to perform...
Have you something to suggest?

Thanks a lot,
Aurelie

snp • 1.7k views
ADD COMMENT • link • modified 4.4 years ago by Bjoern Gruening ♦ 5.1k • written 4.4 years ago by aurelie.renvoise • 10
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gravatar for Bjoern Gruening
4.4 years ago by
Bjoern Gruening ♦ 5.1k
Germany
Bjoern Gruening ♦ 5.1k wrote:

You need to annotate your genome. SNPeff makes a good job and it is in the Tool Shed.

Hope that helps,

Bjoern

ADD COMMENT • link written 4.4 years ago by Bjoern Gruening ♦ 5.1k
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