I have found my galaxy account very useful but every so often I have to download or delete data from that account to be able to do additional analyses. When I requested our Bioinformatics Core people if they could install a Galaxy Instance for our lab on one of their “super” computers (>1200 processor cores and a total of more than 5400 GB of memory), they asked me how much disk space we would need. Since I am not very computer literate and am still fairly new to using Galaxy, I have decided to ask the Galaxy community. The IT guys will take care of the installation and here are my questions:
1. Would a disk capacity of 500 GB be enough for concurrently analyzing say 2 dog whole genome sequences (WGS) with ~15X average coverage (Illumina) from doing QC to calling and comparing variants? What would be the minimum disk capacity required to do the kind of job that I have just described above? (We have >20 WGSs but we will be happy to analyze 2-4 concurrently).
2. I have never used Galaxy anywhere other than from within my account at www.usegalaxy.org. Now, will a Galaxy Instance installed on our “super” computer have the same easy to use interface or we will need to use command language when using our Galaxy Instance?
I hope I have included all the information necessary to get the answer I am looking for. Thank you in advance.