Question: uWSGI mule setup + nginx fails
gravatar for manuel.pasieka
7 months ago by
manuel.pasieka30 wrote:


I am trying to setup a new local (none cluster) galaxy installation based on v18.01 that should serve multiple users.

Reading the galaxy in production documentation and I understood that

uWSGI for web serving with Mules as job handlers + nginx handling proxying of static context and file uploads is the best solution.

Sadly i am unable to get this setup to work.

galaxy and nginx start both fine, without any errors, but i cannot reach the galaxy web server (not on 8080 where galaxy should be served directly, nor on 80 through nginx)

In /var/log/nginx/error.log i can see the error message

*19 connect() to unix:///opt/galaxy/var/uwsgi.sock failed (2: No such file or directory) while connecting to upstream, client:, server: _, request: "GET / HTTP/1.1", upstream: "uwsgi://unix:///opt/galaxy/var/uwsgi.sock:", host ...

In /etc/nginx/sites-enabled/galaxy

server {
    listen 80 default_server;
    listen [::]:80 default_server;
    server_name _;

    # use a variable for convenience
    set $galaxy_root /opt/galaxy;

    # Enable HSTS
    add_header Strict-Transport-Security "max-age=15552000; includeSubdomains";

    # proxy all requests not matching other locations to uWSGI
    location / {
        uwsgi_pass unix:///opt/galaxy/var/uwsgi.sock;
        uwsgi_param UWSGI_SCHEME $scheme;
        include uwsgi_params;

    # serve framework static content
    location /static/style {
        alias $galaxy_root/static/style/blue;
        expires 24h;
    location /static {
        alias $galaxy_root/static;
        expires 24h;
    location /robots.txt {
        alias $galaxy_root/static/robots.txt;
        expires 24h;
    location /favicon.ico {
        alias $galaxy_root/static/favicon.ico;
        expires 24h;

    # serve visualization and interactive environment plugin static content
    location ~ ^/plugins/(?<plug_type>.+?)/(?<vis_name>.+?)/static/(?<static_file>.*?)$ {
        alias $galaxy_root/config/plugins/$plug_type/$vis_name/static/$static_file;
        expires 24;

In galaxy/config/galaxy.yml i set

  http: :8080
  socket: unix:///opt/galaxy/var/uwsgi.sock

the sock file does not exist. Who should create that? the nginx proxy, or galaxy? Any ideas why i cannot reach the webserver?

uwsgi nginx socket • 669 views
ADD COMMENTlink modified 7 months ago by Nate Coraor3.2k • written 7 months ago by manuel.pasieka30
gravatar for Nate Coraor
7 months ago by
Nate Coraor3.2k
United States
Nate Coraor3.2k wrote:

uWSGI should create the socket. However, there's a mistake in the docs. The value of uWSGI's socket option is not a URL, so it should look like this:

    socket: /opt/galaxy/var/uwsgi.sock

I'll submit a correction for the docs - sorry for the inconvenience.

As to why you're not able to reach it on port 8080, have you enabled uWSGI's master mode?

ADD COMMENTlink written 7 months ago by Nate Coraor3.2k

Thank you Nate!

This solved the issue, in addition i can reach the web server ok 8080 as well now!

ADD REPLYlink written 7 months ago by manuel.pasieka30
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