Question: How to determine genome wide Co-occupancy between two transcription factors? by Galaxy main
gravatar for yewenduo
4.1 years ago by
United States
yewenduo60 wrote:


I am currently using Galaxy to analyze several sets of ChIP-Seq datas, including those published and in house generated from my own sample.

When closely looking at two sets of bigWig file of TF binding data in UCSC genome browser, I surprisingly discovered that two of the transcription factors form well overlapped peaks in the promoter region of several genes.

Now I want to do a heat map ploting for genome wide enriched region in one transcription factor and take a look at that generated from another within the same genome X-axis see if it is also enriched. Ho can I do that?

Is there any other bioinformatic assay I could do to determine the extend of co-occupation of two transcription factors?

Thanks  in advance for answering those questions!

chip-seq • 1.4k views
ADD COMMENTlink modified 4.1 years ago by fubar1.1k • written 4.1 years ago by yewenduo60
gravatar for fubar
4.1 years ago by
fubar1.1k wrote:

Not galaxy main, but is probably a good place to start. Failing that, you might try asking these questions to a more general bioinformatics audience such as

ADD COMMENTlink modified 4.1 years ago • written 4.1 years ago by fubar1.1k
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