Question: Sift Analysis Input And Output File
0
Charlotte Gueydan • 20 wrote:
Sometimes when I do a sift analysis, I noticed that the input and
output
alleles are different. I don't understand why and what does it means ?
could you explain it to me ?
For example, here you can see that the input allele is G/A for chr2
(first line) and the output is G/T
*
input file:
chr2 230341630 + G/A
chr2 43881517 + A/T
chr10 115912482 - G/T
chr10 115900918 - C/T
*
output file:
#Chrom Position Strand Allele Codons Transcript ID
Protein ID Substitution Region dbSNP ID SNP Type
Prediction Score Median Info Num seqs at position User Comment
chr2 230341630 + G/T - ENST00000389045
ENSP00000373697 NA EXON CDS rs1803846:A Unknown
Not scored NA NA NA
chr2 43881517 + A/T ATA-tTA ENST00000260605
ENSP00000260605 I230L EXON CDS rs11556157:T Nonsynonymous
TOLERATED 0.47 3.19 7
chr10 115912482 + C/A CGA-CtA ENST00000369285
ENSP00000358291 R179L EXON CDS rs12782946:T Nonsynonymous
TOLERATED 0.06 4.32 2
chr10 115900918 + G/A CAA-tAA ENST00000369287
ENSP00000358293 Q271* EXON CDS rs7095762:T Nonsynonymous
N/A N/A N/A N/A
Regards.
Charlotte Gueydan
--
*Charlotte Gueydan *, PhD.
INSERM/Université Pierre et Marie Curie
Hôpital Tenon - bâtiment de recherche
4, rue de la Chine
75020 Paris cedex 20
tel : 01 56 01 83 75
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modified 7.4 years ago
by
Jennifer Hillman Jackson ♦ 25k
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written
7.4 years ago by
Charlotte Gueydan • 20
