I would like to build the index for human genome to be used as a reference genome in a local instance of Galaxy. The starting point is to obtain the genome files from UCSC through 'ftp' to 'hgdownload.cse.ucsc.edu'.
If I navigate to the ./hg38/bigZips , I would find many different files. I am not sure which one to download.
I was thinking of downloading the individual chromosome files then combine them into one .fa file as I did months ago with the genome mouse Previous post.
But I would like to know what do you think about this and whether you have a better approach.