Question: Re: Question From Ucsc About Snps And Proteins
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Guruprasad Ananda • 230 wrote:
Hi Jen,
"Mutate Codons with SNPs" tool under "Evolution" section on Galaxy
should help to answer this question. If you look at the tool's help
section, it explains the required format of the input dataset. The
input should have start, end, stop and strand co-ordinates for each of
the codons, joined with start, end, stop, strand co-ordinates and
observed SNPs for each of the SNPs. If the user has these data in two
separate files, he can join them using "Join" tool under "Operate on
genomic intervals" section.
The output of the tool will consist of codons in the input mutated
with the respective SNPs. To check if the changes are synonymous or
not, the user can join this output with a tabular file containing the
genetic code using "Join two queries" tool under "Join, subtract and
group" section.
I hope this answers your questions. Please feel free to email us if
you have any further queries.
Also, please send any future Galaxy-related questions to our mailing
list at galaxy-user@bx.psu.edu.
Thanks!
Guru
Galaxy team.
Guruprasad Ananda
Graduate Student
Bioinformatics and Genomics
The Pennsylvania State University
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modified 8.8 years ago
by
Jennifer Jackson • 80
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written
8.8 years ago by
Guruprasad Ananda • 230
